Comparing Allergy, HIT and MCAD

Updated: May 2019

A common question is: “What’s the difference between IgE food allergy, histamine intolerance and mast cell activation?” – because they symptoms often overlap.

Except for IgE food allergy, these conditions are poorly understood so it impossible to differentiate between them. Most clients with these symptoms don’t get an exact label.

The following table highlights the similarities and differences between these conditions. The details are based on our current understanding. As we discussed in the knowledge is like an iceberg video, this understanding will change with new research.

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